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The Isolation of Chlamydia Pneumoniae in Atherosclerosis Patients in Iran by PCR Method تاریخ ثبت : 1392/02/25
طبقه بندي :
Titel : The Isolation of Chlamydia Pneumoniae in Atherosclerosis Patients in Iran by PCR Method
Author : F. Fallah, G. Eslami, M. Bootorabi, B. Kazemi, H. Goudarzi and E. Mazaheri
Journal : Gene Therapy and Molecular Biology
Year : 2006
Volume : 10
Issue : 1
Pages : 109-112
Abstract :

Cardiovascular disease (CAD) is the leading cause of death in developed countries. The cause is multifactorial. A substantial proportion of patients with CAD do not have traditional risk factors. Infectious diseases may play a role in these cases, or they may intensify the effect of the risk factors. The association of CAD and Chlamydia pneumoniae infection is firmly established, but causality is yet to be proven. We investigated their presence in carotid atherosclerotic plaques. 102 plaque atherosclerotic in dead patients were available for examination in Tehran, Iran. The highly sensitive polymerase chain reaction method was employed with primers specific for this agent The presence of Chlamydia DNA was detected in 23 (22%) out of 102 examined samples. The presence of Chlamydia DNA in these patients supports the hypothesis that this agent has an association with atherosclerosis.

 

Keywords : Atherosclerosis, Cardiovascular disease, Chlamydia pneumonia, PCR.
تعداد نمایش : 563 <<بازگشت
 
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